What is Erectile Dysfunction?

Prescribed it.What is Erectile Dysfunction?

Erectile dysfunction (ED), also known as impotence, is the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse. This common men's health condition affects up to 4.3 million men in the UK, with approximately 50-55% of British men aged 40-70 experiencing some degree of erectile dysfunction.

Erectile dysfunction becomes more frequent with age, affecting roughly 40% of men by age 40 and 70% of men by age 70. However, ED can affect men of all ages, including those in their 20s and 30s. The condition can be caused by various factors, including cardiovascular disease, diabetes, high blood pressure, hormonal imbalances, and psychological factors such as stress, anxiety, or relationship concerns.

Experiencing occasional erection problems is normal, but when ED occurs regularly, it can significantly impact your confidence, wellbeing, and intimate relationships. Understanding that erectile dysfunction is a treatable medical condition—not a personal failing—is crucial for seeking appropriate help.

Effective treatment options are available for erectile dysfunction, and addressing underlying health or lifestyle factors can help improve symptoms. If you're experiencing persistent ED, know that you're not alone and that professional support and proven solutions are available to help you regain confidence and enjoy a healthier, more satisfying sex life.

What Causes Erectile Dysfunction?

Prescribed it.What Causes Erectile Dysfunction?

Understanding the Causes of Erectile Dysfunction (ED)

Erectile dysfunction can have multiple causes, often involving a combination of physical, psychological, and lifestyle factors. Understanding these underlying causes is essential for identifying appropriate treatment options and addressing any contributing health issues.

Physical Causes of Erectile Dysfunction

Cardiovascular conditions are among the most common physical causes of ED, affecting 57-64% of men with erectile dysfunction. High blood pressure, high cholesterol, heart disease, and atherosclerosis can reduce blood flow to the penis, making it difficult to achieve or maintain an erection.

Diabetes affects approximately 20% of men with ED and can damage blood vessels and nerves essential for normal erectile function. Being overweight is a factor in 79% of ED cases, as excess weight increases the risk by contributing to diabetes, cardiovascular disease, and hormonal imbalances.

Hormonal imbalances, particularly low testosterone (affecting 4-9% of men with ED), can significantly impact sexual function. Neurological disorders such as multiple sclerosis, Parkinson's disease, stroke, or spinal cord injuries can interfere with nerve signals needed for erections.

Certain medications can cause ED as a side effect, including treatments for high blood pressure, depression, and prostate conditions. Peyronie's disease, affecting 8% of men with ED, involves scar tissue formation in the penis that can cause pain and curvature, leading to erectile difficulties.

Psychological Causes of Erectile Dysfunction

Stress and anxiety from work, financial concerns, or relationship problems can significantly impact sexual performance. Depression affects 10-16% of men with ED and can reduce sexual desire while interfering with the brain's ability to trigger an erection.

Performance anxiety creates a cycle where worrying about sexual performance makes ED worse, even when there's an underlying physical cause. Anxiety affects 15-22% of men with erectile dysfunction, while low self-esteem, guilt, and relationship issues can contribute to or worsen the condition.

Lifestyle and Contributing Factors

Smoking affects 40-70% of men with ED by damaging blood vessels and restricting blood flow to the penis. Excessive alcohol consumption (affecting 47-71% of men with ED) can impair nerve function and lower testosterone levels.

Lack of physical activity is linked to obesity and cardiovascular issues, both of which increase ED risk. Poor diet high in saturated fats and low in fruits and vegetables can contribute to cardiovascular problems and erectile dysfunction.

Sleep disorders affect 54-60% of men with ED, while recreational drug use and certain activities like long-distance cycling may also contribute to the condition.

When to Seek Help for Erectile Dysfunction

It's normal to experience occasional erection problems, but if ED happens frequently or causes distress, it's important to consult a healthcare professional. Early intervention is crucial as ED can be an early warning sign of underlying medical conditions such as diabetes and cardiovascular disease.

Addressing the underlying causes—whether physical, psychological, or lifestyle-related—can significantly improve symptoms and overall wellbeing. Healthcare professionals can provide personalised treatment plans tailored to your specific needs and circumstances.

What Treatment Options Are Available?

Prescribed it.What Treatment Options Are Available?

First-Line Erectile Dysfunction Treatment in the UK
First-line treatment for erectile dysfunction as recommended by UK guidelines are oral PDE-5 inhibitors, which are clinically proven and widely used as initial treatment for ED in the UK. The NHS supports prescribing generic sildenafil and tadalafil for erectile dysfunction, with branded versions like Viagra and Cialis available through private prescription.

Oral PDE-5 Inhibitors Available at Prescribedit

Sildenafil (Viagra, Viagra Connect, Generic Sildenafil)
Sildenafil is the most well-known ED treatment, with up to 82% of men reporting improved erections in clinical trials. Generic sildenafil is available from 50p per tablet, significantly cheaper than branded Viagra which costs over £5 per tablet. Sildenafil typically takes 30-60 minutes to work and lasts approximately 4 hours.

Tadalafil (Cialis, Cialis Daily, Cialis Together)
Tadalafil shows excellent efficacy with up to 86% of men reporting improved erections in clinical trials. The long-lasting effects (up to 36 hours) make it ideal for spontaneity, earning it the nickname "the weekend pill". Tadalafil is available in both daily (5mg) and as-needed (10mg, 20mg) formulations.

Vardenafil (Generic Levitra)
Vardenafil demonstrates an 81% first-dose success rate for vaginal penetration and 70% for maintained erections. This PDE-5 inhibitor is effective for men who may not respond optimally to other treatments.

Avanafil (Spedra)
Avanafil achieves the fastest onset of action (15-30 minutes) among PDE-5 inhibitors, with 74% of men achieving erections sufficient for intercourse. This makes it ideal for men seeking rapid-acting treatment.

Alternative Treatment Options
Alprostadil Cream (Vitaros)
Alprostadil cream achieves 39-67% success rates depending on dosage and is applied directly to the urethra, working within 5-30 minutes. This topical treatment offers an alternative for men who cannot use oral medications.

Alprostadil Injections/Pellets
Alprostadil injections show approximately 80% success rates in clinical studies, though they're not widely used due to the administration method. These treatments are typically reserved for men who don't respond to oral medications.

Vacuum Erection Devices
Vacuum devices achieve approximately 90% mechanical success rates, but have lower patient satisfaction due to complexity. These non-pharmaceutical options can be effective for men seeking drug-free alternatives.

Penile Implants
Penile implants provide near 100% mechanical success but are reserved for severe cases unresponsive to other treatments. This surgical option is considered when other treatments have failed.

Getting Treatment in the UK
You can access erectile dysfunction (ED) treatment in the UK through the NHS, private prescription, or registered online pharmacies like Prescribedit. At Prescribedit, the majority of prescriptions are reviewed and issued by our experienced UK-registered pharmacists, ensuring safe and effective care tailored to your needs. Our confidential online consultation service allows you to receive clinically proven ED treatments, with every order dispensed from a General Pharmaceutical Council (GPhC)-registered pharmacy. Always choose an online pharmacy that is fully regulated in the UK, and make sure prescribers are registered with the appropriate professional bodies, such as the GPhC for pharmacists and the General Medical Council (GMC) for doctors. This guarantees you receive safe, high-quality, and legally compliant care

Frequently asked questions

  • What is erectile dysfunction (ED)?

    Erectile dysfunction (ED), also known as impotence, is the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse. This common men's health condition affects over 4.3 million men in the UK, with approximately 41.5% of British men experiencing some degree of erectile dysfunction. ED becomes more frequent with age, affecting roughly 29.3% of men aged 18-39 and 45.6% of men aged 40 and over.

  • What causes erectile dysfunction (ED)?

    Erectile dysfunction can be caused by multiple factors, often involving a combination of physical, psychological, and lifestyle elements. Physical causes include cardiovascular conditions such as heart disease, diabetes, high blood pressure, and hormonal imbalances. Psychological factors like stress, anxiety, depression, and relationship problems can significantly impact sexual performance. Lifestyle choices including smoking, excessive alcohol consumption, lack of exercise, and poor diet are also major contributing factors. Research shows that 90% of men with ED have underlying physical causes.

  • Is erectile dysfunction common in the UK?

    Yes, erectile dysfunction is extremely common in the UK. Current statistics show that 41.5% to 50-55% of British men aged 40-70 experience some degree of erectile dysfunction. Nearly half of all UK men (48%) report experiencing difficulty getting or keeping an erection, whether always, sometimes, or occasionally. The condition affects approximately 16.5 million men across the UK, making it one of the most prevalent men's health conditions.

  • Can erectile dysfunction be treated effectively?

    Absolutely - erectile dysfunction is highly treatable, with most men responding well to appropriate treatment. Oral PDE-5 inhibitors show success rates of 70-86% in clinical trials. Lifestyle modifications can reduce ED severity by up to 70% long-term for many men. Treatment options range from oral medications and lifestyle changes to vacuum devices, injections, and surgical implants for persistent cases. At Prescribedit, our UK-registered pharmacists provide personalized treatment plans to ensure safe and effective care.

  • What are the most common erectile dysfunction treatments available in the UK?

    The first-line treatments recommended by UK guidelines are oral PDE-5 inhibitors. These include sildenafil (Viagra and generic versions), tadalafil (Cialis), vardenafil (Levitra), and avanafil (Spedra). PDE5 inhibitors are used by 30 million men worldwide for erectile dysfunction treatment. The NHS prescribed almost 3.5 million ED prescriptions in England between September 2023 and August 2024. All these medications are available through Prescribedit following consultation with our experienced pharmacists

  • How quickly do erectile dysfunction medications work?

    Most oral ED medications typically start working within 30 to 60 minutes of taking them. Avanafil (Spedra) has the fastest onset of action, working in as little as 15-30 minutes. Sildenafil and vardenafil generally take 30-60 minutes to become effective. Tadalafil can take 30 minutes to 2 hours but provides longer-lasting effects of up to 36 hours. Individual response times may vary based on factors like food intake, alcohol consumption, and individual metabolism.

  • Are erectile dysfunction treatments safe to use?

    ED treatments are generally safe for most men when prescribed and monitored by qualified healthcare professionals. However, they may not be suitable if you have certain cardiovascular conditions or take specific medications such as nitrates. This is why consultation with a registered prescriber is essential before starting any ED treatment. At Prescribedit, all prescriptions are reviewed by UK-registered pharmacists to ensure treatment safety and suitability for your individual health profile.

  • Can lifestyle changes help improve erectile dysfunction?

    Yes, lifestyle modifications can significantly improve erectile function and may reduce ED severity by up to 70%. Key lifestyle changes include quitting smoking, reducing alcohol intake, exercising regularly, maintaining a healthy diet, and managing stress effectively. Weight loss is particularly beneficial, as 79% of men seeking ED treatment are overweight. Regular physical activity improves cardiovascular health and blood flow, which are essential for normal erectile function.

  • Is erectile dysfunction a sign of other serious health problems?

    Sometimes, erectile dysfunction can be an early warning sign of underlying cardiovascular disease, diabetes, or other health conditions. ED often shares risk factors with heart disease, making it potentially the first symptom of cardiovascular problems. If you experience persistent erectile dysfunction, it's crucial to speak with a healthcare provider for comprehensive health assessment. This evaluation can help identify and address any underlying medical conditions that may be contributing to your ED.

  • Can I discuss erectile dysfunction confidentially with a healthcare professional?

    Absolutely - confidential consultations are available for erectile dysfunction treatment. At Prescribedit, our experienced UK-registered pharmacists and prescribers offer completely confidential consultations and ongoing support. We provide discreet online consultations and discrete packaging for all ED medications delivered across the UK. Our pharmacy is fully regulated by the General Pharmaceutical Council (GPhC), ensuring professional, confidential, and safe treatment. You can access expert advice and proven treatments in a supportive, judgment-free environment.

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